Trintellix (Vortioxetine)

Trintellix (Vortioxetine)

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Trintellix is a medication primarily used to treat major depressive disorder (MDD) in adults. It belongs to the class of drugs known as serotonin modulators and stimulators (SMS), which work by enhancing the activity of serotonin, a neurotransmitter involved in mood regulation.buy Trintellix (Vortioxetine) online

Unlike some antidepressants that primarily inhibit serotonin reuptake, Trintellix works via multiple mechanisms of action, including serotonin reuptake inhibition, receptor activity modulation, and neurotransmitter release enhancement, which may contribute to its efficacy in treating depression.

Fact Table

Formula

C18H22N2S

License

US DailyMed, EU EMA, US FDA

Bioavailability

75%

Legal status

Rx-Only

Chemical Name

Vortioxetine

Elimination half-life

66 hours

Dosage (Strength)

5mg, 10mg, 15mg, 20mg

Pregnancy

Not recommended

Brands

Trintellix

Protein binding

98–99%

PubChem CID

9966051

MedlinePlus

a614003

ChEBI

76016

ATC code

N06AX26

DrugBank

DB09068

KEGG

D10184

Routes of administration

By mouth

 

Directions

 

The usual dosage of Trintellix is 5-20 mg by mouth once daily with or without food.

 

Ingredients

 

The active ingredient in Trintellix is vortioxetine.

Interactions

Common drug-drug interactions may include:

  • Abciximab
  • Abiraterone Acetate
  • Aceclofenac
  • Acemetacin
  • Acenocoumarol
  • Alfentanil
  • Almotriptan
  • Amineptine
  • Amiodarone
  • Amisulpride
  • Amoxapine
  • Amphetamine
  • Amitriptyline
  • Amitriptylinoxide
  • Apalutamide
  • Apixaban
  • Ardeparin
  • Argatroban
  • Aspirin
  • Atazanavir
  • Bemiparin
  • Benzhydrocodone
  • Benzphetamine
  • Betrixaban
  • Bivalirudin
  • Bromfenac
  • Brompheniramine
  • Bufexamac
  • Buprenorphine
  • Bupropion
  • Buspirone
  • Butorphanol
  • Cangrelor
  • Carbamazepine
  • Celecoxib
  • Certoparin
  • Chlorpheniramine
  • Choline Salicylate
  • Cilostazol
  • Citalopram
  • Clomipramine
  • Clonixin
  • Clopidogrel
  • Cocaine
  • Codeine
  • Cobicistat
  • Cyclobenzaprine
  • Dabigatran Etexilate
  • Dacomitinib
  • Dalteparin
  • Danaparoid
  • Darunavir
  • Desipramine
  • Desirudin
  • Desmopressin
  • Desvenlafaxine
  • Dexibuprofen
  • Dexketoprofen
  • Dextroamphetamine
  • Dextromethorphan
  • Dibenzepin
  • Diclofenac
  • Difenoxin
  • Diflunisal
  • Dihydrocodeine
  • Diphenoxylate
  • Dipyridamole
  • Dipyrone
  • Dolasetron
  • Doxepin
  • Drotrecogin Alfa
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Eletriptan
  • Enoxaparin
  • Enzalutamide
  • Epoprostenol
  • Eptifibatide
  • Escitalopram
  • Eslicarbazepine Acetate
  • Ethylmorphine
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenfluramine
  • Fenoprofen
  • Fentanyl
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Fluconazole
  • Flufenamic Acid
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Fondaparinux
  • Fosphenytoin
  • Frovatriptan
  • Gepirone
  • Granisetron
  • Heparin
  • Hydrocodone
  • Hydromorphone
  • Hydroxyamphetamine
  • Hydroxytryptophan
  • Ibuprofen
  • Iloprost
  • Imipramine
  • Indomethacin
  • Iobenguane I 131
  • Ivosidenib
  • Ketobemidone
  • Ketoprofen
  • Ketorolac
  • Lasmiditan
  • Lepirudin
  • Levomilnacipran
  • Levorphanol
  • Linezolid
  • Lisdexamfetamine
  • Lithium
  • Lofepramine
  • Lorcaserin
  • Lornoxicam
  • Loxoprofen
  • Lumacaftor
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Melitracen
  • Meloxicam
  • Meperidine
  • Metoclopramide
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methylene Blue
  • Methylphenidate
  • Milnacipran
  • Mirtazapine
  • Mitotane
  • Morniflumate
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Naproxen
  • Naratriptan
  • Nefazodone
  • Nepafenac
  • Nicomorphine
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Nortriptyline
  • Ozanimod
  • Oliceridine
  • Ondansetron
  • Opipramol
  • Opium
  • Opium Alkaloids
  • Oxaprozin
  • Oxycodone
  • Oxymorphone
  • Oxyphenbutazone
  • Palonosetron
  • Papaveretum
  • Parecoxib
  • Paregoric
  • Parnaparin
  • Paroxetine
  • Phenelzine
  • Phenindione
  • Phenprocoumon
  • Phenylbutazone
  • Phenytoin
  • Piketoprofen
  • Piritramide
  • Piroxicam
  • Pixantrone
  • Pranoprofen
  • Prasugrel
  • Procarbazine
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Protein C
  • Protriptyline
  • Quinidine
  • Rasagiline
  • Remifentanil
  • Reviparin
  • Ritonavir
  • Rofecoxib
  • Safinamide
  • Salicylic Acid
  • Salsalate
  • Selegiline

 

Cautions

 

Use Trintellix with caution if you have a history of suicidal thoughts or behaviors, bipolar disorder, seizures, or liver impairment.

It may increase the risk of suicidal thinking and behavior, particularly in young adults.

Regular monitoring for worsening depression or emergence of suicidal thoughts is recommended during treatment with Trintellix.buy Trintellix (Vortioxetine) online

 

Side Effects

 

Common adverse reactions to Trintellix may include:

  • Abnormal hypersensitivity reaction
  • Constipation
  • Hemorrhage
  • Hyponatremia
  • Nausea
  • Sexual dysfunction
  • Serotonin syndrome
  • Vomiting

Additional Information

Dosage

5mg, 10mg, 15mg, 20mg

Quantity

28 tablets, 84 Tablets

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